Sepsis, Choc septique, ...

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016, Critical Care Medicine: March 2017 - Volume 45 - Issue 3 - p 486–552

IDSA POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines, David N Gilbert, Andre C Kalil, Michael Klompas, Henry Masur, Dean L Winslow, Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2017 November 22

The Surviving Sepsis Campaign: A Rush to Judgment, Daniel J. Pallin, MD, MPH and Rory Spiegel, MD, NEJM Journal Watch, August 3 2018

Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis, The PRISM Investigators* March 21, 2017DOI: 10.1056/NEJMoa1701380

Conclusions: In this meta-analysis of individual patient data, EGDT did not result in better outcomes than usual care and was associated with higher hospitalization costs across a broad range of patient and hospital characteristics

Sepsis Pediatric Packages (PedsPacs), TREKK

Délai antibiotiques

A Systematic Review of the Effect of Delayed Appropriate Antibiotic Treatment on the Outcomes of Patients With Severe Bacterial Infections. Zasowski EJ, Bassetti M, Blasi F, Goossens H, Rello J, Sotgiu G, Tavoschi L, Arber MR, McCool R, Patterson JV, Longshaw CM, Lopes S, Manissero D, Nguyen ST, Tone K, Aliberti S. Chest. 2020 Sep;158(3):929-938. doi: 10.1016/j.chest.2020.03.087. Epub 2020 May 22. PMID: 32446623.

Outcome of Immediate Versus Early Antibiotics in Severe Sepsis and Septic Shock: A Systematic Review and Meta-analysis. Rothrock SG, Cassidy DD, Barneck M, Schinkel M, Guetschow B, Myburgh C, Nguyen L, Earwood R, Nanayakkara PWB, Nannan Panday RS, Briscoe JG. Ann Emerg Med. 2020 Oct;76(4):427-441. doi: 10.1016/j.annemergmed.2020.04.042. Epub 2020 Jun 25. PMID: 32593430.

The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock: A Systematic Review and Meta-Analysis. Sterling SA, Miller WR, Pryor J, Puskarich MA, Jones AE. Crit Care Med. 2015;43(9):1907-1915. doi:10.1097/CCM.0000000000001142


Fluides de réanimation dans le sepsis

Lower vs Higher Fluid Volumes During Initial Management of Sepsis: A Systematic Review With Meta-Analysis and Trial Sequential Analysis, Chest 2020 Jun;157(6):1478-1496. doi: 10.1016/j.chest.2019.11.050. Epub 2020 Jan 23.