Migraine
Effectiveness and Safety of Pharmacologic Therapies for Migraine in the Emergency Department: A Systematic Review and Bayesian Network Meta-analysis. deSouza IS, Anthony N, Thode H Jr, Allen R, Belyavskaya J, Koos J, Singer A. Ann Emerg Med. 2024 Dec 13:S0196-0644(24)01197-1. doi: 10.1016/j.annemergmed.2024.11.004. Epub ahead of print. PMID: 39674934.
Management of Adults With Acute Migraine in the Emergency Department: The American Headache Society Evidence Assessment of Parenteral Pharmacotherapies, Headache, June 2016
Practice Guideline Update: Acute Treatment of Migraine in Children and Adolescents, American Academy of Neurology, August 2019
Clinician Summary
Randomized Trial Comparing Low- vs High-Dose IV Dexamethasone for Patients With Moderate to Severe Migraine, Benjamin W. Friedman, Clemencia Solorzano, Benjamin D. Kessler, Kristina Martorello, Carlo L. Lutz, Carmen Feliciano, Nicole Adler, Hillary Moss, Darnell Cain, Eddie Irizarry, Neurology Oct 2023, 101 (14) e1448-e1454; DOI: 10.1212/WNL.0000000000207648
Discussion: When added to 10 mg IV metoclopramide, doses of dexamethasone greater than 4 mg are unlikely to benefit patients in the ED with migraine.
A Randomized Controlled Trial of Intravenous Haloperidol vs. Intravenous Metoclopramide for Acute Migraine Therapy in the Emergency Department, The Journal of Emergency Medicine, Vol. 49, No. 3, pp. 326–334, 2015
Aspirin in the Treatment and Prevention of Migraine Headaches: Possible Additional Clinical Options for Primary Healthcare Providers. Biglione B, Gitin A, Gorelick PB, Hennekens C. Am J Med. 2019 Nov 9. pii: S0002-9343(19)30966-0. doi: 10.1016/j.amjmed.2019.10.023. [Epub ahead of print] Review. PMID: 31712099
Prévention
Prevention of Episodic Migraine Headache Using Pharmacologic Treatments in Outpatient Settings: A Clinical Guideline From the American College of Physicians. Amir Qaseem, Thomas G. Cooney, Itziar Etxeandia-Ikobaltzeta, et al. Ann Intern Med. [Epub 4 February 2025]. doi:10.7326/ANNALS-24-01052
Comparative Effectiveness of Pharmacologic Treatments for the Prevention of Episodic Migraine Headache: A Systematic Review and Network Meta-analysis for the American College of Physicians. Johanna A.A. Damen, Bada Yang, Demy L. Idema, et al. Ann Intern Med. [Epub 4 February 2025]. doi:10.7326/ANNALS-24-00315
Updated Canadian Headache Society Migraine Prevention Guideline with Systematic Review and Meta-analysis. Medrea I, Cooper P, Langman M, et al. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. Published online 2024:1-23. doi:10.1017/cjn.2024.285