Arthrose

Arthrose - Ostéoarthrite

PEER simplified decision aid: osteoarthritis treatment options in primary care. Lindblad AJ, McCormack J, Korownyk CS, Kolber MR, Ton J, Perry D, Thomas B, Moe S, Garrison S, Dugré N, Chan K, Allan GM. Can Fam Physician. 2020 Mar;66(3):191-193. No abstract available.

Corticostéroïdes Intra-articulaires

Intra-articular Corticosteroid Injections in the Hip and Knee: Perhaps Not as Safe as We Thought? Kompel AJ, Roemer FW, Murakami AM, Diaz LE, Crema MD, Guermazi A. Radiology. Published online Oct 15, 2019. Doi: 10.1148/radiol.2019190341.

Four main adverse joint findings have been structurally observed in patients after IACS injections: accelerated OA progression, subchondral insufficiency fracture, complications of osteonecrosis, and rapid joint destruction, including bone loss. 

Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial. McAlindon TE, LaValley MP, Harvey WF, Price LL, Driban JB, Zhang M, Ward RJ. JAMA. 2017 May 16;317(19):1967-1975. doi: 10.1001/jama.2017.5283. PMID: 28510679; PMCID: PMC5815012.
Conclusions and Relevance : Among patients with symptomatic knee osteoarthritis, 2 years of intra-articular triamcinolone, compared with intra-articular saline, resulted in significantly greater cartilage volume loss and no significant difference in knee pain. These findings do not support this treatment for patients with symptomatic knee osteoarthritis. 

Progression of Knee Osteoarthritis With Use of Intraarticular Glucocorticoids Versus Hyaluronic Acid. Justin BucciXiaoyang ChenMichael LaValleyMichael, Arthritis & rheumatology (Hoboken, N.J.)v74 n2 (202202): 223-226
Conclusion: Intraarticular GC injections are not associated with an increased risk of knee OA progression compared to HA.