Toxicologie

Aide-mémoire guidant les 5 premières minutes de la réanimation toxicologique

Site web, Centre Anti-poison du Québec, incluant les liens vers les Webinaires

Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial. Freund Y, Viglino D, Cachanado M, Cassard C, Montassier E, Douay B, Guenezan J, Le Borgne P, Yordanov Y, Severin A, Roussel M, Daniel M, Marteau A, Peschanski N, Teissandier D, Macrez R, Morere J, Chouihed T, Roux D, Adnet F, Bloom B, Chauvin A, Simon T.  JAMA. 2023 Nov 29:e2324391. doi: 10.1001/jama.2023.24391. Epub ahead of print. PMID: 38019968; PMCID: PMC10687712.

Antidotes:

Les antidotes en toxicologie d'urgence, INSPQ

Acétaminophène

Protocole N-acétylcystéine Centre Antipoison du Québec à compter du 2 décembre 2019

Understanding lactic acidosis in paracetamol (acetaminophen) poisoning, Br J Clin Pharmacol. 2011 Jan; 71(1): 20–28. doi:  10.1111/j.1365-2125.2010.03765.x

Bêtabloqueurs

Intoxication par un bêtabloqueur, CAPQ

Bloqueurs calciques

Intoxication par un bloqueur des canaux calciques, CAPQ;

Intoxication provoquée par une co-ingestion de bêtabloqueurs et de bloqueurs des canaux calciques, CAPQ

Cannabis:

RCEM best practice guideline: suspected cannabinoid hyperemesis syndrome in emergency departments  Humphries C, Gillings M Emergency Medicine Journal Published Online First: 06 March 2024. doi: 10.1136/emermed-2024-213886

Cannabinoid hyperemesis syndrome: clinical trajectories and patterns of use three months following a visit to the emergency department. Rachel S Wightman, Jane Metrik, Timmy R Lin, Alexandra B Collins, Francesca L Beaudoin Academic Emergency Medicine 2023 June 31

SAEM GRACE: Dopamine antagonists and topical capsaicin for cannabis hyperemesis syndrome (CHS) in the emergency department: a systematic review of direct evidence. Monica Sabbineni, William Scott, Kiran Punia, Kriti Manuja, Angad Singh, Kaitryn Campbell, James MacKillop, Iris Balodis Academic Emergency Medicine 2023 June 31

Cannabinoid Hyperemesis Syndrome, Curr Drug Abuse Rev . 2011 December ; 4(4): 241–249

Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Clinical Toxicology 2017 May 11, : 1-6

"Hot sauce" cutanée pour syndrome d'hyperémésie canabinoid, Medscape

Intravenous Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC): A Randomized, Controlled Trial, Ruberto AJ, Sivilotti MLA, Forrester S, Hall AK, Crawford FM, Day AG.Ann Emerg Med. 2020 Nov 5:S0196-0644(20)30666-1. doi: 10.1016/j.annemergmed.2020.08.021. Epub ahead of print. PMID: 33160719.
CONCLUSION: In this clinical trial, haloperidol was superior to ondansetron for the acute treatment of cannabis-associated hyperemesis. The efficacy of haloperidol over ondansetron provides insight into the pathophysiology of this now common diagnosis in many EDs.

Haloperidol, a Novel Treatment for Cannabinoid Hyperemesis Syndrome, American Journal of Therapeutics: January/February 2017 - Volume 24 - Issue 1 - p e64–e67. doi: 10.1097/MJT.0000000000000157

Successful Treatment of Suspected Cannabinoid Hyperemesis Syndrome Using Haloperidol in the Outpatient Setting, Case Rep Psychiatry. 2016; 2016: 3614053. Published online 2016 Aug 11. doi:  [10.1155/2016/3614053]

Cannabis de synthèse contenant de la mort aux rats : des centaines d'hospitalisations aux US, Medscape, 30 juillet 2018

Intubation

Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial. Freund Y, Viglino D, Cachanado M, Cassard C, Montassier E, Douay B, Guenezan J, Le Borgne P, Yordanov Y, Severin A, Roussel M, Daniel M, Marteau A, Peschanski N, Teissandier D, Macrez R, Morere J, Chouihed T, Roux D, Adnet F, Bloom B, Chauvin A, Simon T.  JAMA. 2023 Dec 19;330(23):2267-2274. doi: 10.1001/jama.2023.24391. PMID: 38019968; PMCID: PMC10687712.