Toxicologie

Aide-mémoire guidant les 5 premières minutes de la réanimation toxicologique

Site web, Centre Anti-poison du Québec, incluant les liens vers les Webinaires

Antidotes:

Les antidotes en toxicologie d'urgence, INSPQ

Acétaminophène

Protocole N-acétylcystéine Centre Antipoison du Québec à compter du 2 décembre 2019

Understanding lactic acidosis in paracetamol (acetaminophen) poisoning, Br J Clin Pharmacol. 2011 Jan; 71(1): 20–28. doi: 10.1111/j.1365-2125.2010.03765.x

Cannabis:

Cannabinoid Hyperemesis Syndrome, Curr Drug Abuse Rev . 2011 December ; 4(4): 241–249

Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Clinical Toxicology 2017 May 11, : 1-6

"Hot sauce" cutanée pour syndrome d'hyperémésie canabinoid, Medscape

Intravenous Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC): A Randomized, Controlled Trial, Ruberto AJ, Sivilotti MLA, Forrester S, Hall AK, Crawford FM, Day AG.Ann Emerg Med. 2020 Nov 5:S0196-0644(20)30666-1. doi: 10.1016/j.annemergmed.2020.08.021. Epub ahead of print. PMID: 33160719.
CONCLUSION: In this clinical trial, haloperidol was superior to ondansetron for the acute treatment of cannabis-associated hyperemesis. The efficacy of haloperidol over ondansetron provides insight into the pathophysiology of this now common diagnosis in many EDs.

Haloperidol, a Novel Treatment for Cannabinoid Hyperemesis Syndrome, American Journal of Therapeutics: January/February 2017 - Volume 24 - Issue 1 - p e64–e67. doi: 10.1097/MJT.0000000000000157

Successful Treatment of Suspected Cannabinoid Hyperemesis Syndrome Using Haloperidol in the Outpatient Setting, Case Rep Psychiatry. 2016; 2016: 3614053. Published online 2016 Aug 11. doi: [10.1155/2016/3614053]

Cannabis de synthèse contenant de la mort aux rats : des centaines d'hospitalisations aux US, Medscape, 30 juillet 2018